A unique microenvironment in the developing liver supports the expansion of megakaryocyte progenitors. Brouard N, Jost C, Matthias N, Albrecht C, Egard S, Gandhi P, Strassel C, Inoue T, Sugiyama D, Simmons PJ, Gachet C, Lanza F. Blood Adv. 2017 Sep 26;1(21):1854-1866.
The role of extracellular matrix stiffness in megakaryocyte and platelet development and function. Leiva O, Leon C, Kah Ng S, Mangin P, Gachet C, Ravid K. Am J Hematol. 2018 Mar;93(3):430-441.
Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria. Gaertner F, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa-Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher RT, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt M, Massberg S. Cell. 2017 Nov 30;171(6):1368-1382.e23.
Amotosalen/UVA pathogen inactivation technology reduces platelet activability, induces apoptosis and accelerates clearance. Hechler B, Ravanat C, Gachet C. Haematologica. 2017 Dec;102(12):e502-e503.
Platelet Integrins in Tumor Metastasis: Do They Represent a Therapeutic Target? Lavergne M, Janus-Bell E, Schaff M, Gachet C, Mangin PH. Cancers (Basel). 2017 Sep 28;9(10).
The role of 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors. Ayme-Dietrich E, Lawson R, Côté F, de Tapia C, Da Silva S, Ebel C, Hechler B, Gachet C, Guyonnet J, Rouillard H, Stoltz J, Quentin E, Banas S, Daubeuf F, Frossard N, Gasser B, Mazzucotelli JP, Hermine O, Maroteaux L, Monassier L. Br J Pharmacol. 2017 Nov;174(22):4123-4139.
Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y1 Receptor Downregulation. Shinozaki Y, Shibata K, Yoshida K, Shigetomi E, Gachet C, Ikenaka K, Tanaka KF, Koizumi S. Cell Rep. 2017 May 9;19(6):1151-1164.
Delayed-onset of procoagulant signalling revealed by kinetic analysis of COAT platelet formation. Alberio L, Ravanat C, Hechler B, Mangin PH, Lanza F, Gachet C. Thromb Haemost. 2017 Jun 2;117(6):1101-1114.
Macrothrombocytopenia and dense granule deficiency associated with FLI1 variants: ultrastructural and pathogenic features. Saultier P, Vidal L, Canault M, Bernot D, Falaise C, Pouymayou C, Bordet JC, Saut N, Rostan A, Baccini V, Peiretti F, Favier M, Lucca P, Deleuze JF, Olaso R, Boland A, Morange PE, Gachet C, Malergue F, Fauré S, Eckly A, Trégouët DA, Poggi M, Alessi MC. Haematologica. 2017 Jun;102(6):1006-1016.
Dual role of IL-21 in megakaryopoiesis and platelet homeostasis. Benbarche S, Strassel C, Angénieux C, Mallo L, Freund M, Gachet C, Lanza F, de la Salle H. Haematologica. 2017 Apr;102(4):637-646.
Bioreactivity of stent material: Activation of platelets, coagulation, leukocytes and endothelial cell dysfunction in vitro. Ollivier V, Roques C, Receveur N, Gratz M, Feldman L, Letourneur D, Gachet C, Mangin PH, Jandrot-Perrus M. Platelets. 2017 Sep;28(6):529-539.