Platelet integrin α6β1 controls lung metastasis through direct binding to cancer cell-derived ADAM9. Mammadova-Bach E, Zigrino P, Brucker C, Bourdon C, Freund M, De Arcangelis A, Abrams SI, Orend G, Gachet C, Mangin PH. JCI Insight. 2016 Sep 8;1(14):e88245.
A novel platelet-type von Willebrand disease mutation (GP1BA p.Met255Ile) associated with type 2B « Malmö/New York » von Willebrand disease. Lavenu-Bombled C, Guitton C, Dupuis A, Baas MJ, Desconclois C, Dreyfus M, Li R, Caron C, Gachet C, Fressinaud E, Lanza F. Thromb Haemost. 2016 Nov 30;116(6):1070-1078.
Respective contributions of single and compound granule fusion to secretion by activated platelets. Eckly A, Rinckel JY, Proamer F, Ulas N, Joshi S, Whiteheart SW, Gachet C. Blood. 2016 Nov 24;128(21):2538-2549
Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation. Aguilar A, Pertuy F, Eckly A, Strassel C, Collin D, Gachet C, Lanza F, Léon C. Blood. 2016 Oct 20;128(16):2022-2032.
Inherited dysfunctional platelet P2Y12 receptor mutations associated with bleeding disorders. Lecchi A, Femia EA, Paoletta S, Dupuis A, Ohlmann P, Gachet C, Jacobson KA, Machura K, Podda GM, Zieger B, Cattaneo M. Hamostaseologie. 2016 Nov 7;36(4):279-283.
The contribution of mouse models to the understanding of constitutional thrombocytopenia. Léon C, Dupuis A, Gachet C, Lanza F. Haematologica. 2016 Aug;101(8):896-908. doi: 10.3324/haematol.2015.139394. Review.
Coagulation factors bound to procoagulant platelets concentrate in cap structures to promote clotting. Podoplelova NA, Sveshnikova AN, Kotova YN, Eckly A, Receveur N, Nechipurenko DY, Obydennyi SI, Kireev II, Gachet C, Ataullakhanov FI, Mangin PH, Panteleev MA. Blood. 2016 Sep 29;128(13):1745-55.
Hemostatic properties and protein expression profile of therapeutic apheresis plasma treated with amotosalen and ultraviolet A for pathogen inactivation. Ohlmann P, Hechler B, Chafey P, Ravanat C, Isola H, Wiesel ML, Cazenave JP, Gachet C. Transfusion. 2016 Sep;56(9):2239-47.
Lentiviral gene rescue of a Bernard-Soulier mouse model to study platelet glycoprotein Ibβ function. Strassel C, Bull A, Moog S, Receveur N, Mallo L, Mangin P, Eckly A, Freund M, Dubart-Kupperschmitt A, Gachet C, Lanza F. J Thromb Haemost. 2016 Jul;14(7):1470-9.
Platelets are dispensable for antibody-mediated transfusion-related acute lung injury in the mouse. Hechler B, Maître B, Magnenat S, Heim V, El Mdawar MB, Gachet C, de la Salle H. J Thromb Haemost. 2016 Jun;14(6):1255-67.
Cdc42-dependent F-actin dynamics drive structuration of the demarcation membrane system in megakaryocytes. Antkowiak A, Viaud J, Severin S, Zanoun M, Ceccato L, Chicanne G, Strassel C, Eckly A, Leon C, Gachet C, Payrastre B, Gaits-Iacovoni F. J Thromb Haemost. 2016 Jun;14(6):1268-84.
Standardization of a well-controlled in vivo mouse model of thrombus formation induced by mechanical injury. Tang C, Wang Y, Lei D, Huang L, Wang G, Chi Q, Zheng Y, Gachet C, Mangin PH, Zhu L. Thromb Res. 2016 May;141:49-57.
Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets. Strassel C, Brouard N, Mallo L, Receveur N, Mangin P, Eckly A, Bieche I, Tarte K, Gachet C, Lanza F. Blood. 2016 May 5;127(18):2231-40.